Mandi Schook

Adjunct Assistant Professor

Cleveland Metropark Zoo

Dr. Schook is the Associate Research Curator at Cleveland Metroparks Zoo. She focuses on endocrine and behavioral monitoring of health, welfare, and reproductive biology in wildlife, as well as gamete cryobiology and assisted reproductive techniques. Her research is aimed at optimizing the care of animals in zoos and developing tools to improve population management preserve genetic diversity and ensure the long-term health and viability of endangered populations.  We use a variety of techniques, including enzyme- and radio-immunoassays to monitor hormones in urine, feces, saliva and blood.  Hormones including glucocorticoids, reproductive steroids and metabolic regulators such as insulin and inflammatory cytokines provide insight into the health and welfare status of animals managed in a zoo-environment in relation to factors such as enrichment, diet, and other management practices. In addition, the development of techniques such as semen collection, sperm cryopreservation and artificial insemination allow us to preserve the current genetic diversity of managed populations. Dr. Schook obtained her PhD in Veterinary Science at the University of Kentucky. She is a steering committee member of the AZA Endocrine, Reproduction, and Ambassador Animal Scientific Advisory Groups and a member of the AZA Research & Technology Committee.


Cleveland Metroparks Zoo
4200 Wildlife Way
Cleveland, OH 44118.

Zoo Website:


Selected Publications:

Wagman JD, Wolfe BA and Schook MW.  (Nov 2014).  The effect of fluphenazine decanoate on glucocorticoid production, reproductive cyclicity, and the behavioral stress response in the Persian onager (Equus hemionus onager).  Zoo Biol.  In Review.

Schook MW, Wildt DE, Raghanti MA, Wolfe BA and Dennis PM. (Nov 2014).  Increased inflammation and decreased insulin sensitivity indicate metabolic disturbances in zoo-managed compared to free-ranging black rhinoceros (Diceros bicornis)Gen Comp Endocrinol.  In Review.

Weiss RB, Schook MW and Wolfe BA.  (2014). Long Acting Neuroleptic Use for Reproductive Management in Non Domestic Ungulates Using the Domestic Goat (Capra hircus) as a Model.  Zoo Biol. 33(3):204-211


Capiro JM, Stoops MA, Freeman EW, Clawson D and Schook MW.  (2014). Effects of management strategies on glucocorticoids and behavior in Indian rhinoceros (Rhinoceros unicornis):  Translocation and Operant Conditioning.  Zoo Biol.  33(2):131-143.

Collins CW, Monfort SL, Vick MM, Wolfe BA, Weiss RB, Keefer C and Songsasen, N.  (2014).  Oral and injectable synthetic progestagens effectively manipulate the estrous cycle in the Przewalski’s horse (Equus ferus przewalskii) Anim Reprod Sci. 148(1-2):42-52.

Schook MW, Wildt DE, Weiss RB, Wolfe BA, Archibald KE and Pukazhenthi BS.  (2013). Fundamental studies on the reproductive biology of the endangered Persian onager (Equus hemionus onager) result in first wild equid offspring from artificial insemination.  Biol Reprod.  89(2):41.


Conforti VA, Bateman HL, Schook MW, Newsom J, Lyons LA, Grahn RA, Deddens JA and Swanson WF.  (2013). Laparoscopic oviductal artificial insemination improves pregnancy success in exogenous gonadotropin-treated domestic cats as a model for endangered felids.  Biol Reprod.  89(1):4.


(name change)


Vick MM, Bateman HL, Lambo CA and Swanson WS.  (2012). Improved cryopreservation of domestic cat spermatozoa in a chemically defined medium.  Theriogenol. 78 (9): 2120-2128.

Nielsen BD, Vick MM and Dennis PM. (2012).  A potential link between insulin resistance and iron overload disorder in browsing rhinoceroses investigated through the use of an equine model.  J. Zoo Wildl. Med. 43(3 Suppl): S61-S65.

Ganswindt A, Brown JL, Freeman EW, Kouba AJ, Penfold LM, Santymire RM, Vick MM, Wielebnowski N, Willis EL and Milnes MR.  (2012).  International Society for Wildlife Endocrinology: the future of endocrine measures for reproductive science, animal welfare and conservation biology.  Biol. Lett. 8 (5): 695-697.

Vick MM, Wildt DE, Turner JB, Palme R, Wolfe BA and Pukazhenthi BS.  (2012).   Glucocorticoid response to changes in enclosure size and human proximity in the Persian onager (Equus hemionus onager).  Stress.  15(1): 52-61.

Collins CW, Songsasen N, Vick MM, Wolfe BA, Weiss RA, Keefer CL and Monfort SL. (2012).  Abnormal reproductive patterns in Przewalski’s mares is associated with a loss in gene diversity.  Biol. Reprod.  86 (2): 28.


Graduate Students

Bonnie Baird – Advisor Mandi Vick (Schook)

I am interested in using science to inform animal management and improve welfare in a zoo setting. My research focuses on animals used in education programs in zoos; using behavioral and physiological measures to assess welfare in armadillos, hedgehogs, red-tailed hawks and cheetahs.

Jason Wagman – Advisor Mandi Vick (Schook)

My research focuses on improving animal welfare and management in large mammals using a combination of hormone monitoring and behavioral observations.  Recent projects include looking at the effects of feeding enrichment on activity and exploration in bears, and monitoring the efficacy of long-acting neuroleptics used to reduce handling stress related to reproductive management in Persian onagers.